



Orb Strategic Research



Orb Strategic Research

Investment Landscape Example Report.
Topic: Health-Tech sector.
Date: Jul 2023
Client: Redacted
How this report could be used.
Client could successfully leveraged our data to harness the growing potential of the health-tech sector. This comprehensive understanding of the market could prove instrumental for our client in aligning their business model and investment strategy with the changing landscape.
Introduction:
The UK healthcare industry is more complex than that of other countries, mainly due to its unique health and life science ecosystem. The NHS, which refers to the Government-funded medical and health care services accessible to all UK residents without an upfront payment, plays a vital role in maintaining service quality. It provides a national research and evidence-gathering platform with unique data and clinical insights, contributing to significant scientific breakthroughs that drive the development of life-changing treatments, technologies, and services. To ensure efficiency and effectiveness in NHS services, various regulatory bodies are in place to monitor and assess health service quality provided by both public and private providers. Consequently, there is a substantial annual demand for healthcare investment to support the NHS.
UK Healthcare Trends
According to the Chief of NHS England's interview, the NHS is currently facing a plethora of challenges. Three key challenges and their proposed solutions are:
- An aging population leading to growing health inequality as more care is required to support older individuals. To address this, the NHS must focus on preventing illnesses rather than solely treating them.
- The increasing digital demand and workforce crisis are causing difficulties in efficiently delivering NHS services. Insufficient doctors and nurses are leading to significantly longer patient waiting times than before. To tackle this issue in the short and long term, it is essential not only to value the existing healthcare staff but also to improve the technology they use, thus reducing their workload.
- Funding shortages persist despite increased funding from the UK government. When considering inflation and comparing funding levels with other European countries' healthcare industries, it becomes apparent that the NHS's funding remains inadequate. To adapt to this challenge, the UK government encourages NHS collaboration with private sector organisations, providing more opportunities for global investors to invest in the UK healthcare industry.
Besides these internal challenges, the UK healthcare sector is also grappling with external challenges, including the remains of the pandemic and the impact of climate change, which may introduce potential new fatal diseases in the UK. Post-lockdown regulations have influenced existing and emerging healthcare trends, particularly regarding health equity and digital health technologies. Patients' expectations and behaviours towards healthcare are shifting towards less time-consuming, more efficient, and accurate services. These challenges have led to an increase in European investors' interest in the UK and Irish Healthcare sectors.
Overview of Healthcare Industry
The healthcare sector is vast and intricate, intersecting with numerous other industries involved in the provision and coordination of medical and related goods and services. Healthcare is recognized as one of the 11 S&P sectors/GICS commonly used in finance by Capital Market. Within the healthcare sector, two industry groups and six distinct industries can be identified. These are healthcare equipment and services, and pharmaceuticals, biotechnology and services (see Figure 1.).
This complex landscape can be simplified into three main buckets:
Digital Healthtech: primarily focuses on prevention and monitoring rather than treatment. It involves the application of organized knowledge and skills through devices, medicines, vaccines, procedures, and systems designed to solve health problems and enhance quality of life. Healthtech primarily revolves around personal health, empowering patients to engage with their health outside of hospital settings, such as through telehealth and remote monitoring. As the UK's population ages, Healthtech plays a crucial role in effectively addressing this demographic shift.
Medtech: this category’s primary goal is to improve people's health through diagnosis, patient care, treatment, and improvement. It is mainly used within hospitals to diagnose and treat patients, rather than focusing solely on prevention. The main investments in Medtech include equipment, devices, machines, software, and tools. In 2023, the global Medtech market is expected to reach almost $600 billion. According to UK government data, investment in Medtech increased by £477 million from 2014 to 2019, with a further 97% increase observed from 2020 to 2022, highlighting the urgency to accelerate this process due to the pandemic.
Biotech: this category is the intersection of technology and biology, primarily focused on creating new drugs and predicting their effects on people based on cell information, genetic testing, and artificial tissue growth. While Biotech typically requires larger funds for research and development, mid-market investors often follow the biotech market news to gain insights into the healthcare industry.
Overview of Healthcare Industry
The UK healthcare industry is a large target. It has a combined size of almost $55 billion, with MedTech receiving $30 billion revenue, biotech $20 billion, and digital Healthtech $4 billion. Each of these markets are formed by a mixture of large international businesses, mid-sized established firms, and innovative startups. The NHS is the largest UK customer across each category, contributing up to 85% of revenue across some segments. This is creating a new opportunity for businesses that can help to tackle the NHS’ challenges.
The UK is already recognized as one of the world's healthtech innovation hubs, with leading companies such as AstraZeneca and GlaxoSmithKline having helped to build the UK ecosystem. The Association of British Healthtech industries states that there are 4,060 healthtech businesses in UK employing more than 130,000 people. These businesses range from consumer facing apps such as PushDoctor, that has raised $44m to provide digital on-demand GP consultations to Lumeon whose innovative Care Journey Orchestration assists healthcare firms to improve the delivery of their services.
These companies have attracted significant investment. Investment Monitor estimates that VC investment into UK healthtech has gone from $420 million in 2016, to USD 3.8 billion in 2022. This growth was buoyed by the pandemic that saw significant capital flow to businesses tackling COVID-19. Each sub-segment of UK healthtech have varying investment landscapes and trends.
Medtech: This category has seen rapid growth over the last few years. There was a 204% increase in the number of MedTech companies in UK from 2020 to 2022, and startup investment increased by 96% according to a report by Beauhurst. Notable UK Medtech companies include CMR Surgical, Quanta, and Osler Diagnostics, which have collectively secured over £1 billion in funding. CMR Surgical stands out, having raised £744 million over ten equity rounds and received investment from multiple funds, including Switzerland-based LGT Capital Partners and ABB Technology Ventures. The company has been featured in six high-growth lists, most notably the BusinessCloud MedTech 50.
Biotech: UK Biotech has always been a strong sector, with strong support from world class universities such as Oxford and Cambridge, distribution channels made by UK headquartered Pharma giants such as GSK, and high levels of investment. There was a high peak of investment in 2021 with £4.5 billion investment, but this dropped off in 2022 where investment only reached £1.8 billion. Notable UK midmarket biotech firms include: Artios Pharma, who raised £245 million across 5 equity funding rounds to develop cancer treatments that target DNA damage response, investors included Arix Bioscience, CRT Pioneer Fund, Pfizer Venture Investments and SV Health Investors, and; Touchlight, who raised £147 million, to develop its DNA manufacturing technology with investors including Downing, Novator Partners and Bridford Investments.
Digital Healthtech: The UK has gained recognition as Europe's healthtech Silicon Valley, playing an essential role in the global healthcare sector. Between 2016 and 2021, the UK's 'Golden Triangle' (comprising London, Oxford, and Cambridge) witnessed 508 healthtech startups receiving funding from venture capital investors. Notably, 7 out of 47 UK unicorns are in the healthtech sector. Two notable successful healthtech startups are Huma and Cera Care. Huma provides applications that integrate health data from existing hospital databases, as well as patient wearables and other mobile devices, securely transmitting this information for use by doctors. In April 2020, Huma acquired two British healthtech companies, BioBeats and Tarilian Laser Technologies, to shift its focus from monitoring patients to gathering biological data for future health issue prevention. On the other hand, Cera Care is a digital-first healthcare at home company delivering care, nursing, telehealth, and repeat prescriptions services in people's homes via technology. Cera Care successfully reduced the hospitalization rate by 52% and predicted up to 80% of hospitalizations seven days in advance.
Future of UK Healthtech
According to The UK Government Healthcare Policy Report, there are three main investment strategies in UK healthcare: Predictive, Preventive, and Personalized. The future healthcare system will be vastly different from today, with individuals gaining a deeper understanding of their genetic profile and health risks. Each of these present an opportunity for investors.
Data plays a pivotal role in achieving the goals of preventing diseases and providing personalized health data for individuals. It requires a massive health database supported by AI-powered analytics tools that work seamlessly together to ensure the quality of outcomes. Therefore, digital transformation enabled by interoperable data, AI, and open, secure platforms will be the driving force behind much of the healthcare system's change.
Diagnostics 4.0 refers to smarter hospital equipment enabled by machine learning to alert clinicians about patients' early symptoms. The widespread digitalization, supported by appropriate infrastructure, will revolutionize clinical diagnostics, benefiting both clinicians and patients.
Considering the serious shortage of healthcare staff in the UK, care robots could revolutionize the care system and provide additional support. As one in seven people in the UK is expected to be over 75 years old by 2040, there is a substantial demand for care robots to assist the elderly more easily with their daily care without increasing pressure on care staff.

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